The computational genomics community has come increasingly to rely on the methodology of creating annotations of scientific literature using terms from controlled structured vocabularies such as the Gene Ontology (GO). We here address the question of what such annotations signify and of how they are created by working biologists. Our goal is to promote a better understanding of how the results of experiments are captured in annotations in the hope that this will lead to better representations of biological reality through (...) both the annotation process and ontology development, and in more informed use of the GO resources by experimental scientists. (shrink)

According to the cognitivist strategy, the desire to bring about P provides reasons for intending to bring about P in a way analogous to how perceiving that P provides reasons for believing that P. However, while perceiving P provides reasons for believing P by representing P as true, desiring to bring about P provides reasons for intending to bring about P by representing P as good. This paper offers an argument against this view. My argument proceeds via an appeal to (...) what I call the non-substitutability of perception, the thesis that, given that there is no independent evidence for P, one cannot substitute something that fails to provide reasons with respect to P for the perceptual experience that P, without altering the rational permissibility of believing that P. By contrast, I argue that it is always possible to substitute something that fails to provide reasons for a desire without altering the rational permissibility of an intention based on said desire. I take this to show that a desire does not provide reasons in a way analogous to perceptual experience. (shrink)

My dissertation addresses the question "do desires provide reasons?" I present two independent lines of argument in support of the conclusion that they do not. The first line of argument emerges from the way I circumscribe the concept of a desire. Complications aside, I conceive of a desire as a member of a family of attitudes that have imperative content, understood as content that displays doability-conditions rather than truth-conditions. Moreover, I hold that an attitude may provide reasons only if it (...) has truth-evaluable content. Insofar as desires lack truth-evaluable content, I hold that the content of a desire has the wrong kind of logical structure to provide reasons. My second line of argument claims that even if a desire did have truth-evaluable content, it would not follow that desires provide reasons. This is because a desire has no more rational significance than a guess or coin-flip. My argument relies on what I call the non-substitutability principle, the thesis that (all things being equal) one cannot substitute something that lacks rational significance, relative to some attitude, A, for something that has rational significance, relative to A, and leave the rational standing of A unchanged. For example, one cannot substitute the guess that P (i.e., something that lacks rational significance relative to the belief that P) for the perception that P (i.e., something that is rationally significant relative to the belief that P) without altering the rational standing of the belief. I argue that when the non-substitutability principle is applied to a desire that gives rise to an intention, it turns out that one can always substitute a guess or coin-flip (i.e., something that lacks rational significance relative to the intention) for the desire, without altering the rational standing of the intention. I take this to show that desires are not rationally significant relative to the intentions to which they give. (shrink)

Currently, the widely used notion of activity is increasingly present in computer science. However, because this notion is used in specific contexts, it becomes vague. Here, the notion of activity is scrutinized in various contexts and, accordingly, put in perspective. It is discussed through four scientific disciplines: computer science, biology, economics, and epistemology. The definition of activity usually used in simulation is extended to new qualitative and quantitative definitions. In computer science, biology and economics disciplines, the new simulation activity definition (...) is first applied critically. Then, activity is discussed generally. In epistemology, activity is discussed, in a prospective way, as a possible framework in models of human beliefs and knowledge. (shrink)

In the Panathenaic Games, there was a torch race for teams of ephebes that started from the altars of Eros and Prometheus at Plato’s Academy and finished on the Acropolis at the altar of Athena, goddess of wisdom. It was competitive, yes, but it was also sacred, aimed at a noble goal. To win, you needed to cooperate with your teammates and keep the delicate flame alive as you ran up the hill. Likewise, Plato’s philosophy combines competition and cooperation (...) in pursuit of the goal of wisdom. On one level, agonism in Plato is explicit: he taught in a gymnasium and featured gymnastic training in his educational theory. On another level, it is mimetic: Socratic dialogue resembles intellectual wrestling. On a third level, it is metaphorical: the athlete’s struggle illustrates the struggle to be morally good. And at its highest level, it is divine: the human soul is a chariot that races toward heaven. This volume explores agonism in Plato on all of these levels, inviting the reader—as Plato does—to engage in the megas agōn of life. Once in the contest, as Plato’s Socrates says, we’re allowed no excuses. (shrink)

Hill explains that this book “is written both for non-philosophers and for students of philosophy. It is intended to say something both about philosophy, particularly applied moral philosophy, and about the argument for vegetarianism” (p. xiv). Since vegetarianism is an important topic in applied ethics, I had high expectations of this work. However, although the writing is commendably clear, and despite the fact that it is to be welcomed as the first book to bring together and discuss at some (...) length four different arguments for adopting a vegetarian diet, this book is disappointing both by philosophical and scholarly standards. (shrink)

ABSTRACT The individual-community relationship has always been one of the most fundamental topics of social sciences. In sociology, this is known as the micro-macro relationship while in economics it refers to the processes, through which, individual actions lead to macroeconomic phenomena. Based on philosophical discourse and systems theory, many sociologists even use the term "emergence" in their understanding of micro-macro relationship, which refers to collective phenomena that are created by the cooperation of individuals, but cannot be reduced to individual actions. (...) "Emergence" theories attempt to explain the nature of society as a complex system by examining how individuals and their relationships lead to the creation of integrated and macro-social phenomena such as markets, educational systems, cultural beliefs, and shared social practices. As a prelude to activity, every researcher has to answer the question from the methodological point of view, how is it possible to study the behavior of social groups and how can we gain knowledge about the laws related to social groups? Anyone who deals with humanities and social sciences or any reality and phenomenon that affects human beings, inevitably deals with the reality that is emerging. In fact, emergence occurs when one level of reality emerges radically from another level. Examples of emergent levels of reality include how the mind emerges from the body; or the way society emerges from human beings. Therefore, when there is an emerging factor, different scientific disciplines should be used, because it is inevitable to talk about social affairs, psychology and neurobiology, as well as physical and even chemical. -/- INTRODUCTION Since its beginning in the 19th century, sociology has faced the fundamental question of what a social phenomena stands for? At a glance, sociologists deal with the study of social groups, collective behavior, institutions, social structures, social networks, and social dynamics, and ultimately all such phenomena are composed of individuals. Therefore, social phenomena seem to have no independent ontological status, and in this case, sociology is ultimately about reducible individuals. Different approaches about the micro-macro relationship, using the concept of "emergence", argue that although collective phenomena are created by individuals, they cannot be reduced to individual action. The term "emergence" is used to distinguish "emergent results" from " Procedural results". Results are called Procedural that can only be calculated by adding or subtracting the causes that act together. On the contrary, they are emergent outcomes that are qualitatively novel compared to the causes from which they originate. An example of such emergent results is mental characteristics that emerge from neural processes, but are not considered among the characteristics of neural processes of components - which are their origin. Philosophical debates about emergentism and reductionism focus on the mind-brain relationship, but as many philosophers have noted, they can be generalized to apply to any hierarchical set of features. The cognitive revolution reactivated a 19th century controversy between theorists of Identity and dualism. The theorists of Identity believe in reductionist materialism and elimination of metaphysics, according to which the mind is nothing more than the biological, while the dualists believe that the mind and the brain are distinct from each other. Emergence has been considered as a third way between the theories of Identity and dualism. -/- METHODOLOGY Interdisciplinarity Is fundamentally indicated by the dominance of open systems as well as social and emerging systems at different levels. Therefore, as long as we are facing a new emergentism, there will necessarily be different fields and an interdisciplinary method. The commonality of social sciences and cognitive sciences on the issue of emergence provides the possibility of interaction and exchange of concepts between these two for deeper research. Therefore, in this research, apart from the concepts of Subvenience and downward causation, we have used multiple realization and wildly disjunctive, which are used to explain the emerging concept in cognitive sciences, including neurobiology, psychology, and philosophy. For analytical and interdisciplinary approaches, after examining the concepts of subvenience, and wildly disjunctive, Individualistic and collectivist emergentism have been reviewed. And then their adequacy is criticized and evaluated in meeting strong emergence conditions. -/- FINDINGS Philosophers of the mind have been able to define the conditions of irreducibility and downward causation, which are essential for strong emergence, by using the principle of subvenience with the help of multiple realization and wildly disjunctive principles. Therefore, by definition, emergentist individualism suffers from the problem of how to explain downward causality and irreducibility, and emergentist collectivism faces the challenge of reification. The analysis of the challenges facing the two methodological approaches of individualism and collectivism leads us to three unresolved issues about the emerging phenomenon, which are realism, downward causality, and mechanism. Despite the differences in the stances of these two approaches regarding the aforementioned triple problems, individualists and collectivists both agree that some social characteristics are reducible; and some others are irreducible due to their complexity, the determination of which, depends on the case study of the mechanism of emergence of each social characteristic. -/- CONCLUSION An emergence that is consistent with reductionism is called a weak emergence. And strong emergence includes the principle of irreducibility and downward causality. According to strong emergence, the characteristics of social phenomena have downward causal power, which cannot be reduced to the causal forces. The principle of subvenience, together with multiple realization and wildly disjunctive, can provide the conditions of irreducibility and downward causality, which are essential conditions of strong emergence. Based on the philosophical analysis of two methodological approaches, individualist and collectivist, it can be concluded that emergentist individualism suffers from the problem of how to explain downward causality and irreducibility, and reification collectivism faces the challenge of reification. The analysis of the problems faced by these two approaches leads us to three unresolved issues, which are realism, downward causality, and mechanism. individualist emergentists acknowledge the existence of emergent social characteristics, but despite this, they believe that these characteristics are not real but merely analytical constructs that require explanation based on individuals and their mutual actions. But collectivists argue that emergentism yields a categorical ontology and supports social realism. They accept the dependence of social characteristics on individuals, but claim that social entities and structures are ontologically independent. Individualists and collectivists both agree that some social characteristics are reducible; and others are irreducible due to their complexity; and the only way to recognize this is to engage in empirical studies of the mechanisms and temporal processes of "emergence" that create social characteristics. -/- NOVELTY The newness of this compact article is as follows: a) Presenting an interdisciplinary approach using the analysis of philosophy of cognitive sciences, including the philosophy of mind, neurobiology and psychology to formulate the issue of social emergence; b) Criticizing individualist and collectivist methodological approaches to the issue of social emergence and explaining the sufficiency and shortcomings of both in providing weak and strong emerging conditions; c) Explaining and categorizing the challenges facing methodological approaches in explaining the phenomenon of social emergence, in three categories: realism, downward causality, and mechanism. BIBLIOGRAPHY Beckermann, A., Flohr, H., & Kim, J. (eds.) (1992). Emergence or reduction? Essays on the prospects of nonreductive physicalism. Berlin: Walter de Gruyter. Bhaskar, R. (1979). The possibility of Naturalism. New York: Routledge. Bhaskar, R., Danermark, B. & Price, L. (2018). Interdisciplinarity and wellbeing: A critical realist general theory of interdisciplinarity. London and New York: Routledge. Blau, P.M. (1981). Introduction: diverse views of social structure and their common denominator. In Blau, P.M. & Merton, R.K. (eds.), Continuity in Structural Inquiry (pp. 1–23). Beverly Hills: Sage. Blau, P.M. (1987). Microprocess and macrostructure. In K.S. Cook (ed.), Social Exchange Theory (pp. 83–100). Newbury Park, CA: Sage. Brooks, R.A., & Maes, P. (eds). (1994). Artificial life IV; proceedings of the Fourth International Workshop on the Synthesis and Simulation of Living Systems. Cambridge, Mass: MIT Press. Clark, A. (1997). Being there: Putting brain, body, and world together again. Cambridge, Mass.: MIT Press. Coleman, J. S. (1987). Microfoundations and macrosocial behavior. In: J. C. Alexander, B. Giesen, R. Munch, & Neil J. Smelser (Eds.). The Micro-Macro Link (pp. 153–73). Berkeley: University of California. Coleman, J. S. (1990). Foundations of social theory. Cambridge, MA: Harvard University Press. Elster, J. (1985). Making sense of Marx. New York: Cambridge University Press. Fodor, J.A. (1974). Special sciences (Or: The disunity of science as a working hypothesis). Synthese, 28(2), 97–115. Fodor, J.A. (1989). Making mind matter more. Philosophical Topics, 17, 59-79. Giddens, A. (1984). The constitution of society: Outline of the theory of structuration. Berkeley: University of California Press. Hempel, C.G. (1965). Aspects of scientific explanation and other essays in the philosophy of science. New York: The Free Press. Horgan, T. (1993). From supervenience to superdupervenience: meeting the demands of a material world. Mind, 102, 555-586. Humphreys, P. (1997). How properties emerge”. Philosophy of Science, 64, 1-17. Kim, J. (1999). Making sense of emergence. Philosophical Studies, 95, 3–36. Kincaid, H. (1997). Individualism and the unity of science. New York: Rowman & Littlefield. Lewis, D.K. (1986). The plurality of worlds. Oxford: Oxford University Press. Nigel, G., & Conte, R. (eds.) (1995). Artificial societies; The computer simulation of social life. London: UCL Press. O’Connor, T. (1994). Emergent properties. American Philosophical Quarterly, 31, 91-104. Popper, K.R. (1968). Conjectures and refutations: The Growth of Scientific Knowledge. New York: Harper & Row. Sawyer, R. K. (2001). Emergence in sociology: contemporary philosophy of mind and some implications for sociological theory. American Journal of Sociology, 107, 551-585. Sawyer, R. K. (2004). The mechanisms of emergence. Philosophy of the Social Sciences, 34, 260–282. Sawyer, R. K. (2005). Social emergence: societies as complex systems. Cambridge: Cambridge University Press. Sawyer, R.K. (2003). Nonreductive individualism: Part 2, Social causation. Philosophy of the Social Sciences, 33, 203–224. Winch, P. (1993). The idea of a social science and its relation to philosophy‭ (SAMT, Trans.). Tehran, Iran: SAMT. (shrink)

Mark Coeckelbergh starts his book with a very powerful picture based on a real incident: On the 9th of January 2020, Robert Williams was wrongfully arrested by Detroit police officers in front of his two young daughters, wife and neighbors. For 18 hours the police would not disclose the grounds for his arrest (American Civil Liberties Union 2020; Hill 2020). The decision to arrest him was primarily based on a facial detection algorithm which matched Mr. Williams’ driving license photo (...) with the picture of a man who was suspected of watch theft two years earlier. Not only did the computer ‘get it wrong’ as one of the detectives said, when Mr. Williams made them aware that the picture of the suspect obviously wasn’t resembling him, the probably unreliable algorithm very likely contributed to racial discrimination (Hill 2020). It is well documented that many available facial detection algorithms at this time had significant problems (e.g. a comparably high false positive rate) with respect to black persons, like Mr. Williams (NIST 2019). Multiple causes may exist, such as unbalanced training datasets and insufficient optimization. Coeckelbergh compares the disturbing case of Mr. Williams with a political interpretation of Franz Kafka’s The Trial, where the protagonist, Josef K., is accused of an unspecified crime by an opaque, oppressive and absurd bureaucracy: “In the 21st-century United States, Josef K. is black and is falsely accused by an algorithm, without explanation” (p. 2). (shrink)

Tradução para o português de "Uma espécie de história de minha vida" (A kind of history of my life), ou Carta a um médico (A Letter to a Physician), uma carta escrita por Hume (1711-1776), endereçada em março ou abril de 1734 a um médico não identificado (segundo Norton provavelmente John Arbuthnot ou George Cheyne), na qual Hume pede alguns conselhos para continuar com o seu trabalho filosófico. O título atual é extraído do primeiro parágrafo.A carta foi escrita em 1734, (...) um pouco antes de Hume viajar para Bristol, onde, “forçado a fazer uma rápida incursão em uma vida mais ativa”, conforme relata em sua autobiografia Minha vida, buscou empregar-se no comércio. A importância dessa carta reside no seu caráter autobiográfico e nos comentários que Hume faz sobre seu projeto filosófico. A carta foi publicada originalmente em Life and correspondence of David Hume, John Hill Burton(Ed.), Edinburgh 1846, v. 1, p. 30-39; ela foi reproduzida em The Letters of David Hume. Grey, J. Y. T. (ed.) Oxford: Clarendon Press, 1932, 2v; v.1, n.3, p. 12-18, e pode ser encontrada também em The Cambridge companion to Hume, David Fate Norton, Jacqueline Taylor (ed.) 2 ed. Cambridge University Press, 2009, p. 515-522. Para essa tradução consultamos o texto original conforme apresentado nas duas últimas edições aqui mencionadas. (shrink)

RESUMO A bovinocultura sempre esteve atrelada ao desenvolvimento do Brasil e, pensando no avanço, as exigências da máxima eficiência nos sistemas de criação foi pautada na forma de como conseguir realizar a reprodução de bovinos com ênfase na eficiência econômica e reprodutiva. O objetivo deste trabalho é elucidar as principais biotecnologias que auxiliam na maior produtividade reprodutiva de bovinos. Dessa forma, o estudo foi realizado usando artigos do banco de dados do Google acadêmico e SciELO, além de livros do acervo (...) pessoal e sites oficiais. Com o manejo reprodutivo aplicado na bovinocultura, é possível identificar pontos a serem melhorados e implantação de práticas que auxiliam no incremento da eficiência reprodutiva como a estação de monta, que concentra a fertilização dos animais em uma determinada época do ano, o uso do índice de escore corporal, o qual consegue determinar a viabilidade da vaca a ser fertilizada, e a identificação da idade a puberdade, na qual a novilha com 60% de peso vivo quando adulta pode estar apta para reprodução, indicando que a nutrição é um fator importante para reduzir o intervalo entre partos, bem como na indução da precocidade, que ainda pode ser maximizada por uso de bioestimuladores. Assim como a implantação do uso de biotecnologias, que podem adicionar aos planteis, indivíduos geneticamente superiores, saudáveis e eficientes. Dentre as biotecnologias, a inseminação artificial é a mais usada no Brasil, com capacidade de fertilizar vacas com sêmen de touros de genética superior, nacional ou importado. Podem ser citadas ainda as técnicas de transferência de embriões e produção in vitro de embriões como tecnologias a serviço do desenvolvimento da eficiência reprodutiva. A utilização de protocolos hormonais no ciclo estral objetiva a sincronização do estro das vacas para facilitar o emprego das biotecnologias. São vários os protocolos usados para essa finalidade, sendo Ovsynch a base de GnRH e prostaglandina com até 50% de eficácia, protocolos à base de estradiol e progesterona com eficácia de até 86,6%, e protocolos que usam gonadotrofina coriônica equina (eCG), indicados para animais magros por condicionar maior diâmetro folicular, o qual é relacionado com aumento na taxa de prenhez. Dessa maneira, as práticas e tecnologias citadas neste estudo são usadas na reprodução assistida de bovinos. PALAVRAS-CHAVE: Criopreservação. Estro. Gestação. Hipófise. Nutrição. ABSTRACT Cattle farming has always been linked to Brazil’s development and, thinking about advancement, the requirements for maximum efficiency in breeding systems was based on how to achieve the reproduction of cattle with an emphasis on economic and reproductive efficiency. The objective of this work is to elucidate the main biotechnologies that help in the greater reproductive productivity of cattle. Thus, the study was done using articles from the Academic Google and SciELO databases, as well as books from the personal collection and official websites. With the reproductive management applied in cattle farming, it is possible to identify points to be improved and implement practices that help to increase reproductive efficiency, such as the breeding season, which concentrates the fertilization of animals at a certain time of year, use of the body score index, which can determine the viability of the cow to be fertilized, identification of age at puberty, in which the heifer with 60% live weight as an adult may be suitable for reproduction, indicating that nutrition is an important factor in reducing the interval between births, as well as in inducing precocity, which can still be maximized by the use of biostimulators. As well as the implementation of the use of biotechnology, which can add genetically superior, healthy and efficient individuals to the breeding stock. Among the biotechnologies, artificial insemination is the most used in Brazil, with the capacity to fertilize cows with superior genetic bull semen, whether national or imported. Embryo transfer techniques and in vitro embryo production can also be cited as technologies in the service of the development of reproductive efficiency. The use of hormonal protocols in the estrous cycle aims at synchronizing the estrus of cows to facilitate the use of biotechnologies. There are several protocols used for this purpose, with Ovsynch being based on GnRH and prostaglandin with up to 50% efficacy, protocols based on estradiol and progesterone with efficacy of up to 86.6%, and protocols that use equine chorionic gonadotropin (eCG), indicated for lean animals because they condition larger follicular diameter, which is related to an increase in the pregnancy rate. Thus, the practices and technologies mentioned in this study can help the assisted reproduction of cattle. KEYWORDS: Cryopreservation. Estro. Gestation. Hypophysis. Nutrition. -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- ALENCAR, M.M. Perspectivas para o melhoramento genético de bovinos de corte no Brasil. In: Embrapa Pecuária Sudeste-Artigo em anais de congresso (ALICE). In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 41., 2004, Campo Grande, MS. Palestras... Campo Grande: SBZ, 2004, p. 358-367., 2004. ALVES, H.A.G. Otimização da produtividade económica e reprodutiva de uma exploração de bovinos de carne. Dissertação de mestrado em Medicina Veterinária no Curso de Mestrado em Medicina Veterinária, conferido pela Universidade Lusófona de Humanidades e Tecnologias, 2014. AZEVEDO, C. et al. O protocolo hormonal ovsynch e suas modificações em vacas leiteiras de alta produção: uma revisão. Archivos de zootecnia, v. 63, n. 241, p. 173- 187, 2014. BARBOSA, C.F. et al. Inseminação artificial em tempo fixo e diagnóstico precoce de gestação em vacas leiteiras mestiças. Revista Brasileira de Zootecnia, v. 40, p. 79- 84, 2011. BARBOSA, F.A. et al. Produtividade e eficiência econômica de sistemas de produção de cria, recria e engorda de bovinos de corte na região sul do estado da Bahia. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 62, p. 677-685, 2010. BARBOSA, R.T.; MACHADO, R. Panorama da inseminação artificial em bovinos. Embrapa Pecuária Sudeste-Documentos (INFOTECA-E), 2008. BARREIROS, T.R.R. et al. Dynamics of follicular growth and progesterone concentrations in cyclic and anestrous suckling Nelore cows (Bos indicus) treated with progesterone, equine chorionic gonadotropin, or temporary calf removal. Theriogenology, v. 81, n. 5, p. 651-656, 2014. BARUSELLI, P.S. et al. Evolução e perspectivas da inseminação artificial em bovinos. Revista Brasileira de Reprodução Animal, v. 43, n. 2, p. 308-314, 2019. BATISTELLA, M. et al. Geotecnologias e gestão territorial da bovinocultura no Brasil. Revista Brasileira de Zootecnia, v. 40, p. 251-260, 2011. BERLITZ, C.G.B. Impacto do estresse ambiental na reprodução de bovinos de corte. Trabalho de Conclusão em Medicina Veterinária. Universidade Federal do Rio Grande Do Sul, 2019. BORDINHON, S.G. Aspectos gerais das fases de cria e recria de bovinos leiteiros. Trabalho de Conclusão de Curso. Curso Medicina Veterinária, Universidade Federal De Santa Catarina, 2021. CAMARGO, L.M. et al. Influência dos escores de condição corporal e da heterose sobre os resultados da inseminação artificial em tempo fixo. Revista Eletrônica Biociências, Biotecnologia e Saúde, v. 10, n. 19, p. 7-16, 2017. CAMPOS, C.C. et al. Gonadorelin at the outset and/or end of an ovulation synchronization progesterone estradiol benzoate-based protocol in Nellore females. Semina: Ciências Agrárias, v. 37, n. 1, p. 173-181, 2016. CARNEIRO JR, J.M.; DE ASSIS, G.M.L. Objetivos e critérios de seleção em bovinos de corte em fase de cria. Embrapa Acre-Artigo de divulgação na mídia (INFOTECA-E), 2016. CARRIJO, M.S.; LINHARES, W.D.; BARCELOS, K.A. Descrição do manejo produtivo, reprodutivo e sanitário de 10 rebanhos leiteiros localizados em 7 municípios do estado de Goiás. Pubvet, v. 2, n. 28, p. 279-294, 2008. CASTRO, S.V. et al. Agentes crioprotetores intracelulares: características e utilização na criopreservação de tecido ovariano e oócitos. Acta Scientiae Veterinariae, v. 39, n. 2, p. 1-17, 2011. CEREZETTI, M.B. et al. Alternativas Para Substituição Do Uso De Implantes Vaginais De Progesterona Na Inseminação Artificial Em Tempo Fixo Em Bovinos. Revista de Ciência Veterinária e Saúde Pública, v. 6, n. 2, p. 416-433, 2019. CEZAR, I.M. et al. Sistemas de produção de gado de corte no Brasil: uma descrição com ênfase no regime alimentar e no abate. Campo Grande, MS: Embrapa Gado de Corte, 2005. COLAZO, M.G.; MAPLETOFT, R. Fisiología del ciclo estral bovino. Ciencia Veterinaria, v. 16, n. 2, p. 31-46, 2017. CONERA, VII. Manejo reprodutivo de bovinos: potencialidade e desafios. Acta Veterinaria Brasilica, v. 8, p. 317-319, 2014. CUNHA, J.M. et al. Aspectos Fisiológicos Do Ciclo Estral Em Bovinos. In: Anais Colóquio Estadual de Pesquisa Multidisciplinar (ISSN-2527-2500) & Congresso Nacional de Pesquisa Multidisciplinar. 2019. CUNHA, R.R. et al. Inseminação artificial em tempo fixo em primíparas Nelore lactantes acíclicas. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 65, p. 1041-1048, 2013. CUNNINGHAM, J. Tratado de fisiologia veterinária. Elsevier Health Sciences, 2011. Da Silva, E. I. C. (2022). Fisiologia da Reprodução de Bovinos Leiteiros: Aspetos Básicos e Clínicos (1st ed.). Belo Jardim. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia do ciclo estral dos animais domésticos. Emanuel Isaque Cordeiro da Silva, 2021. DA SILVA, Emanuel Isaque Cordeiro. Puberdade e Estacionalidade Reprodutiva dos Animais. 2020a. DA SILVA, Emanuel Isaque Cordeiro. Reprodução Animal: Inseminação Artificial. 2020b. DA SILVA, Emanuel Isaque Cordeiro. Transferência de Embriões nos Animais e a Indústria de Embriões no Brasil. 2020c. D’AVILA, C.A. et al. Hormônios utilizados na indução da ovulação em bovinos–Artigo de revisão. Revista Brasileira de Reprodução Animal, v. 43, n. 4, p. 797-802, 2019. DAVIDSON, A.P.; STABENFELDT, G.H. Controle do desenvolvimento gonadal e dos gametas. Tratado de fisiologia veterinária (Cunningham), p. 408-415, 2014. DIAS, E.A.R. et al. O uso de ECG influencia a taxa de concepção em vacas Nelore de diferentes condições corporais submetidas ao mesmo protocolo de IATF?. Boletim de Indústria Animal, v. 70, n. 3, p. 215-220, 2013. DYCE, K.M.; SACK, W.O.; WENSING, C.J.G. Tratado de anatomia veterinária. 4.ed. Rio de Janeiro: Elsevier, 2010. FERNANDES, A.F.A.; OLIVEIRA, J.A.; QUEIROZ, S.A. Escore de condição corporal em ruminantes. Ars Veterinaria, v. 32, n. 1, p. 55-66, 2016. FERRAZ, P.A. et al. Dinâmica folicular e taxa de concepção de vacas Nelore sincronizadas com diferentes protocolos de indução da ovulação. Archives of Veterinary Science, v. 18, n. 4, 2013. FERREIRA, R.M. et al. Synchronization treatments previous to natural breeding anticipate and improve the pregnancy rate of postpartum primiparous beef cows. Theriogenology, v. 114, p. 206-211, 2018. FILHO, L.C.C. et al. Fatores que interferem na eficiência reprodutiva de receptoras de embrião bovino. Arq. Ciênc. Vet. Zool., v. 16, n. 2, p. 201-208, 2013. FONSECA, R.S. Manejo nutricional, reprodutivo e biotécnicas para incrementar a eficiência reprodutiva em rebanhos de vacas de corte. Dissertação de Mestrado. Universidade Federal de Viçosa, 2018. FONSECA, V.O. et al. Parâmetros reprodutivos de touros Nelore (Bos taurus indicus) criados a pasto, em de diferentes faixas etárias. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 71, p. 385-392, 2019. FONTES, A.R.C. Transferência de Biotecnologia. Revista Online de Pesquisa: Propriedade Intelectual, v. 2, n. 2, p. 98-110, 2019. GALVÃO, A.L.C.O. Fertilidade de touros e suas interações com fatores relacionados as fêmeas em programas de inseminação artificial em tempo fixo. Tese de Doutorado. Universidade de São Paulo, 2021. GOTTSCHALL, C.S. et al. Avaliação do desempenho reprodutivo de vacas de corte lactantes submetidas à IATF a partir da aplicação do GnRH, da manifestação estral, da reutilização de dispositivos intravaginais e da condição corporal. Acta Scientiae Veterinariae, v. 40, n. 1, p. 1-10, 2012. GOTTSCHALL, C.S. et al. Influência da indução à puberdade e do peso vivo sobre a resposta reprodutiva em novilhas de corte. Revista Veterinária em Foco, v. 16, n. 2, 2019. GOUVEIA, F.F. A Produção in vitro de embriões bovinos. Monografia (Trabalho de Conclusão de Curso) – Faculdade de Agronomia e Veterinária, Universidade de Brasília, Brasília, 2011. GUASTI, P.N.; MONTEIRO, G.A.; PAPA, F.O. Componentes do plasma seminal e sua influência sobre a criopreservação e fertilidade de espermatozoides equinos. Veterinária e Zootecnia, v.19, n.2, p.169-180, 2012. GUIMARÃES, J.D. et al. Seleção e manejo reprodutivo de touros zebu. Revista Brasileira de Zootecnia, v. 40, p. 379-388, 2011. HAFEZ, E.S.E. Reprodução Animal, 7 ed. São Paulo: Manole Ltda, 2004. HARTMANN, W. et al. Influência do escore de trato reprodutivo e da circunferência escrotal dos touros sobre a antecipação da puberdade em novilhas Nelore. Tuiuti: ciência e cultura, v. 7, n. 62, p. 140-165, 2021. HILL, R.W.; WYSE, G.A.; ANDERSON, M. Fisiologia Animal-2. Artmed Editora, 2016. KONIG, H.E.; LIEBICH, H.G. Anatomia dos animais domésticos. 6ª ed. Porto Alegre: Artmed, 2016. LEITE, P.A. et al. Criopreservação do sêmen bovino. Journal of Health Sciences, v. 13, n. 4, 2011. LUSTOSA, A.A. et al. 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FROM THE HISTORY OF PHYSICS TO THE DISCOVERY OF THE FOUNDATIONS OF PHYSICS By Antonino Drago, formerly at Naples University “Federico II”, Italy – drago@unina,.it (Size : 391.800 bytes 75,400 words) The book summarizes a half a century author’s work on the foundations of physics. For the forst time is established a level of discourse on theoretical physics which at the same time is philosophical in nature (kinds of infinity, kinds of organization) and formal (kinds of mathematics, kinds of logic). (...) This double side of the two dichotomies assures a deep comprehension of theoretical physics by avoiding both a purely philosophical analysis and a purely formal analysis, each manifestly insufficient for representing all the aspects of theoretical physics. Among the many formulations of a physical theory, e.g. Mechanics, also Mach(1) recognized technical differences only, Instead my suggestion is to consider their differences as revealing the characteristic features of their foundations. No more radical differences may exist than those concerning both their kinds of Mathematics and their kinds of Logic. As a fact, after the 20th Century within each of these sciences there exist two antagonist foundations, within Mathematics either the classical one or the constructive one(2); within Mathematical Logic either the classical logic or the intuitionist one(3). Let us take Mechanics as an instance. Being the choices of the Newton’s formulation respectively the actual infinity of the differential equations relying on the infinitesimals and the classical logic, a formulation based on the alternative choices is Lazare Carnot’s,(4) whose mathematics is no more than algebraic-trigonometric and the logic is the intuitionist one, because this formulation makes use of doubly negated propositions, whose corresponding affirmative propositions are idealistic or false; i.e. in these cases the law of double negation fails, as in intuitionist logic occurs. By considering these two dichotomies as the foundations of the physical theories, each couple of choices upon them fashions one out four models of scientific theory, which are baptized through the authors of their most representative theories: Newtonian, Carnotian, Lagrangian, Descartesian. In correspondence four versions of the principle of inertia are recognized, as suggested by respectively: Descartes. Lazare Carnot, Enriques and Cavalieri.(5) All that suggests that the four models of scientific theory may be graphically represented as a compass orientating our minds amid the so numerous physical theories. By taking these dichotomies as interpretative categories, a new interpretative history of Physics including both classical and modern physics results according to a quadrilinear development. The birth of modern physics is characterized by the two theories - Einstein’s paper on special relativity and Einstein’s first paper on quanta - whose choices are the alternative ones to those of the previously dominant physical theory, Newtonian mechanics: in the latter paper Einstein i) declares the dichotomy on the kinds of mathematics (“Introduction”) and then he chooses the discrete mathematics; ii) by using doubly negated propositions he organizes his theory in an alternative way to the deductive-axiomatic one.(6) Moreover, a new history of Philosophy of knowledge results. Kant’s first two a priori transcendental categories represent the physical interpretation of the two choices out of the four pairs of choices on the two dichotomies, i.e. the choices of the dominant theory of mechanics, Newton’s. Hegel’s dialectic was a misleading attempt of anticipating the subsequent intuitionist logic. The book starts by a comparison of different formulations of thermodynamics in order to recognize the first dichotomy on the kind of organization. In chapter 2 the dichotomy on the kind of infinity is recognized through a comparison of Newrton’s mechanics and Lazare Carnot’s. A quickly history of the other classical physical theories is illustrated in chapter 3; it results a foundational conflict between the last two theories, and hence a conflict between their opposite couples of choices. The two main theories of modern physics, special realtivity and quantum mechanics confirm the foundational role played by the two dichotomies which gives reason for the radical change in the history of theoretical physics. Indeed, the opposition of the two main pairs of choices gives reason of the crisis in theoretical physics in the early 1900s. As a global result, the book represents the first interpretation of the entire history of Physics, both classical and modern; This fact proves that the four models of scientific theories can works as a compass (that of the front cover) suggesting a direction among the many physical theories. This new history of physics leads to re-visit both Koyré’s and Kuhn’s historiographies. Their interpretative categories are interpreted and explained through the two dichotomies so that it is possible to suggest à la Koyré categories based on the alternative choices theories to Newton’s as the suitable categories for interpreting the alternative theories to Newton’s mechanics. All that suggests a new interpretation of the crucial step in the history of Western philosophy of knowledge, i.e. the passage from Leibniz to Kant: Leibniz’s suggestion of the two labyrinths of human minds may be seen as a close anticipation of the two above dichotomies. Kant applied them in order to construct the well-known four cosmological proofs, which however he misinterpreted as leading to contradictions, instead to tow different methods of investigation corresponding to the two different kinds of logic.(7) Bibliography 1. Mach E. (1883), Die Mechanik, Leipzig: Brockhaus, Chap. IV, Sect. III. 2. Bishop E. (1967), Constructive Analysis, New York: Mc Graw-Hill. 3. Heyting A. (1962), Intuitionism. An Introduction, Amsterdam: North-Holland. 4. L. Carnot (1783), Essai on the Machines en général, Defay, Dijion (Enlish translation: Springer, Berlin, 2020). Drago A. (2004), “A new appraisal of old formulations of mechanics”, Am. J. Phys., 72(3), pp. 407-9. 5. Vella M.R. (2007), “Le quattro versioni del principio di inerzia”, in M. Leone et al. (eds.), L’eredità di Fermi, Majorana e altri Temi. Napoli: ESI, pp. 147-151. 6. Drago A. (2014), “The emergence of two options from Einstein°s first paper on Quanta”, in Pisano R., Capecchi D., Lukesova A. (eds.), Physics, Astronomy and Engineering. Critical Problems in the History of Science and Society, Scientia Socialis P., Siauliai, 2013, pp. 227-234. 7. This and all in the above points are illustrated by the book Drago A. (2017), Dalla Storia della Fisica ai Fondamenti della Scienza, Roma: Aracne. (shrink)

In a series of recent papers, Jane Friedman has argued that attitudes like wondering, enquiring, and suspending judgement are question-directed and have the function of moving someone from a position of ignorance to one of knowledge. Call such attitudes interrogative attitudes. Friedman insists that all IAs are governed by the following Ignorance Norm: Necessarily, if one knows Q at t, then one ought not have an IA towards Q at t. However, I argue that key premisses in Friedman’s argument actually (...) point towards an opposing conclusion; namely, that IAs are not governed by the Ignorance Norm, and IAs have functions other than moving someone from a position of ignorance to one of knowledge. I conclude that the Ignorance Norm should be rejected. (shrink)

The second essay of Nietzsche's Genealogy of Morality (GM) offers a naturalistic and developmental account of the emergence of conscience, a faculty uniquely responsive to remembering and honoring obligations. This article attempts to solve an interpretive puzzle that is invited by the second essay's explanation of nonmoral obligation, prior to the capacity to feel guilt. Ostensibly, Nietzsche argues that the conscience and our concept of obligation originated within contractual (“creditor-debtor”) relations, when creditors punished delinquent debtors (GM II:5). However, this interpretation, (...) which I call the contractualist reading, is incoherent and subject to an insoluble bootstrapping problem. I argue instead that Nietzsche provides two accounts of nonmoral obligation in the second essay, and that the conscience originated in the morality of custom to track rule prohibitions (“I will nots” [GM II:3]), which Nietzsche conceives of as involuntary or reciprocal obligations that, unlike contractual debts, do not require the making of promises. (shrink)

Richard Holton has argued that the traditional account of intentions—which only posits the existence of all-out intentions—is inadequate because it fails to accommodate dual-plan cases; ones in which it is rationally permissible for an agent to adopt two competing plans to bring about the same end. Since the consistency norms governing all-out intentions prohibit the adoption of competing intentions, we can only preserve the idea that the agent in a dual-plan case is not being irrational if we attribute to them (...) a pair of partial intentions. I argue that, contrary to initial appearances, (i) Holton has yet to offer us an actual account of partial intentions, and (ii) that the traditional account of intentions already has the resources necessary to accommodate dual-plan cases. (shrink)

I argue that the concept of direction of fit is best seen as picking out a certain inferential property of a psychological attitude. The property in question is one that believing shares with assuming and fantasizing and fails to share with desire. Unfortunately, the standard analysis of DOF obscures this fact because it conflates two very different properties of an attitude: that in virtue of which it displays a certain DOF, and that in virtue of which it displays certain revision (...) conditions. I claim that the latter corresponds with the aim of an attitude, not its DOF. In order to remedy this failure of the standard analysis, I offer an alternative account of DOF, which I refer to as the two-content analysis. (shrink)

According to the Strong Belief Thesis (SBT), intending to X entails the belief that one will X. John Brunero has attempted to impugn SBT by arguing that there are cases in which an agent intends to X but is unsure that she will X. Moreover, he claims that the standard reply to such putative counterexamples to SBT – namely, to claim that the unsure agent merely has an intention to try – comes at a high price. Specifically, it prevents SBT (...) from playing the kind of explanatory role the cognitivist requires. This article meets Brunero's challenge to SBT by offering an account of trying and intending to try that not only saves SBT from Brunero's criticism, but does so in a way that preserves the explanatory significance that cognitivists typically take SBT to have. (shrink)

This paper examines the ontological and epistemological implications of artificial intelligence (AI) through posthumanist philosophy, integrating the works of Deleuze, Foucault, and Haraway with contemporary computational methodologies. It introduces concepts such as negative augmentation, praxes of revealing, and desedimentation, while extending ideas like affirmative cartographies, ethics of alterity, and planes of immanence to critique anthropocentric assumptions about identity, cognition, and agency. By redefining AI systems as dynamic assemblages emerging through networks of interaction and co-creation, the paper challenges traditional dichotomies such (...) as human versus machine and subject versus object. Bridging analytic and continental philosophical traditions, the analysis unites formal tools like attribution analysis and causal reasoning with the interpretive and processual methodologies of continental thought. This synthesis deepens the understanding of AI’s epistemic and ethical dimensions, expanding philosophical inquiry while critiquing anthropocentrism in AI design. The paper interrogates the spatial foundations of AI, contrasting Euclidean and non-Euclidean frameworks to examine how optimization processes and adversarial generative models shape computational epistemologies. Critiquing the reliance on Euclidean spatial assumptions, it positions alternative geometries as tools for modeling complex, recursive relationships. Furthermore, the paper addresses the political dimensions of AI, emphasizing its entanglements with ecological, technological, and sociopolitical systems that perpetuate inequality. Through a politics of affirmation and intersectional approaches, it advocates for inclusive frameworks that prioritize marginalized perspectives. The concept of computational qualia is also explored, highlighting how subjective-like dynamics emerge within AI systems and their implications for ethics, transparency, and machine perception. Finally, the paper calls for a posthumanist framework in AI ethics and safety, emphasizing interconnectivity, plurality, and the transformative capacities of machine intelligence. This approach advances epistemic pluralism and reimagines the boundaries of intelligence in the digital age, fostering novel ontological possibilities through the co-creation of dynamic systems. (shrink)

This paper examines the ontological and epistemological implications of artificial intelligence (AI) through posthumanist philosophy, integrating the works of Deleuze, Foucault, and Haraway with contemporary computational methodologies. It introduces concepts such as negative augmentation, praxes of revealing, and desedimentation, while extending ideas like affirmative cartographies, ethics of alterity, and planes of immanence to critique anthropocentric assumptions about identity, cognition, and agency. By redefining AI systems as dynamic assemblages emerging through networks of interaction and co-creation, the paper challenges traditional dichotomies such (...) as human versus machine and subject versus object. Bridging analytic and continental philosophical traditions, the analysis unites formal tools like attribution analysis and causal reasoning with the interpretive and processual methodologies of continental thought. This synthesis deepens the understanding of AI’s epistemic and ethical dimensions, expanding philosophical inquiry while critiquing anthropocentrism in AI design. The paper interrogates the spatial foundations of AI, contrasting Euclidean and non-Euclidean frameworks to examine how optimization processes and adversarial generative models shape computational epistemologies. Critiquing the reliance on Euclidean spatial assumptions, it positions alternative geometries as tools for modeling complex, recursive relationships. Furthermore, the paper addresses the political dimensions of AI, emphasizing its entanglements with ecological, technological, and sociopolitical systems that perpetuate inequality. Through a politics of affirmation and intersectional approaches, it advocates for inclusive frameworks that prioritize marginalized perspectives. The concept of computational qualia is also explored, highlighting how subjective-like dynamics emerge within AI systems and their implications for ethics, transparency, and machine perception. Finally, paper calls for a posthumanist framework in AI ethics and safety, emphasizing interconnectivity, plurality, and the transformative capacities of machine intelligence. This approach advances epistemic pluralism and reimagines the boundaries of intelligence in the digital age, fostering novel ontological possibilities through the co-creation of dynamic systems. (shrink)

The purpose of this study is to develop a system of corporate ethics based on an understanding and interpretation of the ethical demand of human beings who are in relation with each other according to Emmanuel Levinas' teachings and the responsibility the human being has to and for herself and others whom she encounters based on Paul Ricoeur's teachings on human action, text and hermeneutics. While the philosophies to which we will be referring may not overtly present a normative ethic, (...) we shall convey them in such a way that is reasonably germane to the development of our system of corporate ethics that would, indeed, demonstrate why (and, perhaps, how in some instances) the human being must act in response to the demand of the other whom she encounters. -/- We must not abandon the discussion as it relates to the economy but rather include it in a broader and more comprehensive dialogue about working to promote, support and protect the human dignity of all people using the advancements of technology to improve the human condition. The broader discussion must include but not be limited to developing a working definition of corporate ethics. To engage in discussions about the economy as an indicator for human success, we must speak openly and honestly about all stakeholders that participate and are affected by the economy. Without forsaking other stakeholders, we find the corporation - the entity whose actions have the farthest reaching and, in some cases, longer lasting impact on the human condition - to be an appropriate point of departure for this endeavor. (shrink)

We address the ethics of scenarios in which one party entraps, intentionally tempts or intentionally tests the virtue of another. We classify, in a new manner, three distinct types of acts that are of concern, namely acts of entrapment, of intentional temptation and of virtue testing. Our classification is, for each kind of scenario, of itself neutral concerning the question whether the agent acts permissibly. We explain why acts of entrapment are more ethically objectionable than like acts of intentional temptation (...) and why these, in turn, are more ethically objectionable than like acts of virtue testing. Along the way, we scrutinize, and eventually reject, the view that acts of entrapment are ethically unacceptable because intentional temptation is involved in entrapment. (shrink)

In 2011, a 5,000-year-old “male” skeleton buried in a “female” way was discovered by an archaeological team just outside of modern-day Prague. This article queries the impulse to name such a discovery as evidence of transgender identity, and bodies, in an increasingly ancient past. To do so, it takes up the work of Denise Ferreira da Silva, Sylvia Wynter, and Hortense Spillers as a means to push back against the impetus to name such discoveries “transgender” in order to shore up (...) the legitimacy of contemporary trans identity. Each of these three thinkers offers a different vantage point for rethinking such naming practices that push the reader to consider how desires to name and place “transgender” in a distant past papers over the violence of plantation slavery, global imperialism, and the Enlightenment's shift toward scientific reason. This article argues not that such anthropological discoveries should not be considered transgender, but rather that the desire for them to be, or become, transgender does not legitimate contemporary transgender identity, and may instead treat certain iterations of transness as spatially and temporally universal. (shrink)

In the first chapter of his Knowledge and Lotteries, John Hawthorne argues that thinkers do not ordinarily know lottery propositions. His arguments depend on claims about the intimate connections between knowledge and assertion, epistemic possibility, practical reasoning, and theoretical reasoning. In this paper, we cast doubt on the proposed connections. We also put forward an alternative picture of belief and reasoning. In particular, we argue that assertion is governed by a Gricean constraint that makes no reference to knowledge, and that (...) practical reasoning has more to do with rational degrees of belief than with states of knowledge. (shrink)

For any essential property God has, there is an ability He does not have. He is unable to bring about any state of affairs in which He does not have that property. Such inabilities seem to preclude omnipotence. After making trouble for the standard responses to this problem, I offer my own solution: God is not omnipotent. This may seem like a significant loss for the theist. But I show that it is not. The theist may abandon the doctrine that (...) God is omnipotent without scaling back the extent of His power and without denying that He has all perfections. (shrink)

Governments are increasingly making use of field experiments to evaluate policy interventions in the spheres of education, public health and welfare. However, the research ethics literature is largely focused on the clinical context, leaving investigators, institutional review boards and government agencies with few resources to draw on to address the ethical questions they face regarding such experiments. In this article, we aim to help address this problem, investigating the conditions under which informed consent is required for ethical policy research conducted (...) or authorized by government. We argue that investigators need not secure participants' informed consent when conducting government policy experiments if: the government institution conducting or authorizing the experiment possesses a right to rule over the spheres of policy targeted by the research; and data collection does not involve the violation of participants' autonomy rights. (shrink)

Under a ‘dirty hands’ model of undercover policing, it inevitably involves situations where whatever the state agent does is morally problematic. Christopher Nathan argues against this model. Nathan’s criticism of the model is predicated on the contention that it entails the view, which he considers objectionable, that morally wrongful acts are central to undercover policing. We address this criticism, and some other aspects of Nathan’s discussion of the ‘dirty hands’ model, specifically in relation to state entrapment to commit a crime. (...) Using János Kis’s work on political morality, we explain three dilemmatic versions of the ‘dirty hands’ model. We show that, while two of these are inapplicable to state entrapment, the third has better prospects. We then pursue our main aim, which is to argue that, since the third model precludes Nathan’s criticism, a viable ‘dirty hands’ model of state entrapment remains an open possibility. Finally, we generalize this result, showing that the case of state entrapment is not special: the result holds good for policing practices more generally, including such routine practices as arrest, detention, and restraint. (shrink)

In The Future of Human Nature, Jürgen Habermas raises the question of whether the embryonic genetic diagnosis and genetic modification threatens the foundations of the species ethics that underlies current understandings of morality. While morality, in the normative sense, is based on moral interactions enabling communicative action, justification, and reciprocal respect, the reification involved in the new technologies may preclude individuals to uphold a sense of the undisposability of human life and the inviolability of human beings that is necessary for (...) their own identity as well as for reciprocal relations. Engaging with liberal bioethics and Catholic approaches to bioethics, the article clarifies how Habermas’ position offers a radical critique of liberal autonomy while maintaining its postmetaphysical stance. The essay argues that Habermas’ approach may guide the question of rights of future generations regarding germline gene editing. But it calls for a different turn in the conversation between philosophy and theology, namely one that emphasizes the necessary attention to rights violations and injustices as a common, postmetaphysical starting point for critical theory and critical theology alike. In 2001, Jürgen Habermas published a short book on questions of biomedicine that took many by surprise.[1] To some of his students, the turn to a substantive position invoking the need to comment on a species ethics rather than outlining a public moral framework was seen as the departure from the “path of deontological virtue,”[2] and at the same time a departure from postmetaphysical reason. Habermas’ motivation to address the developments in biomedicine had certainly been sparked by the intense debate in Germany, the European Union, and internationally on human cloning, pre-implantation genetic diagnosis, embryonic stem cell research, and human enhancement. He turned to a strand of critical theory that had been pushed to the background by the younger Frankfurt School in favor of cultural theory and social critique, even though it had been an important element of its initial working programs. The relationship of instrumental reason and critical theory, examined, among others, by Max Horkheimer, Theodor W. Adorno, and Herbert Marcuse and taken up in Habermas’ own Knowledge and Interest and Theory of Communicative Action became ever-more actual with the development of the life sciences, human genome analysis, and genetic engineering of human offspring. Today, some of the fictional scenarios discussed at the end of the last century as “science fiction” have become reality: in 2018, the first “germline gene-edited” children were born in China.[3] Furthermore, the UK’s permission to create so-called “three-parent” children may create a legal and political pathway to hereditary germline interventions summarized under the name of “gene editing.”In this article, I want to explore Habermas’ “substantial” argument in the hope that philosophy and theology become allies in their struggle against an ever-more reifying lifeworld, which may create a “moral void” that would, at least from today’s perspective, be “unbearable”, and for upholding the conditions of human dignity, freedom, and justice. I will contextualize Habermas’ concerns in the broader discourse of bioethics, because only by doing this, his concerns are rescued from some misinterpretations.[1] Jürgen Habermas, The Future of Human Nature.[2] Ibid., 125, fn. 58. 8[3] Up to the present, no scientific publication of the exact procedure exists, but it is known that the scientist, Jiankui He, circumvented the existing national regulatory framework and may have misled the prospective parents about existing alternatives and the unprecedented nature of his conduct. Yuanwu Ma, Lianfeng Zhang, and Chuan Qin, "The First Genetically Gene‐Edited Babies: It's “Irresponsible and Too Early”," Animal Models and Experimental Medicine ; Matthias Braun, Meacham, Darian, "The Trust Game: Crispr for Human Germline Editing Unsettles Scientists and Society," EMBO reports 20, no. 2. (shrink)

Immanuel Kant is known for his ideas about duty and morally worthy acts, but his conception of virtue is less familiar. Nevertheless Kant’s understanding of virtue is quite distinctive and has considerable merit compared to the most familiar conceptions. Kant also took moral education seriously, writing extensively on both the duty of adults to cultivate virtue and the empirical conditions to prepare children for this life-long responsibility. Our aim is, first, to explain Kant’s conception of virtue, second, to highlight some (...) distinctive and potentially appealing features of the Kantian account of virtue, third, to summarize and explain Kant’s prescriptions for educating young children and youth as well as the duty of moral self-improvement that he attributes to all adults, and, fourth, to respond to some common objections that we regard as misguided or insubstantial. (shrink)

If moral properties lacked causal powers, would moral skepticism be true? I argue that it would. Along the way I respond to various arguments that it would not.

By drawing attention to these facts and to the relationship between Cantor’s and Husserl's ideas, I have tried to contribute to putting Frege's attack on Husserl "in the proper light" by providing some insight into some of the issues underling criticisms which Frege himself suggested were not purely aimed at Husserl's book. I have tried to undermine the popular idea that Frege's review of the Philosophy of Arithmetic is a straightforward, objective assessment of Husserl’s book, and to give some specific (...) reasons for thinking that the uncritical reading of Frege's review has unfairly distorted philosophers' perception of a work they do not know very well. (shrink)

This is a transcript of a conversation between P F Strawson and Gareth Evans in 1973, filmed for The Open University. Under the title 'Truth', Strawson and Evans discuss the question as to whether the distinction between genuinely fact-stating uses of language and other uses can be grounded on a theory of truth, especially a 'thin' notion of truth in the tradition of F P Ramsey.

The fourteen essays in this volume, by leading scholars in the field, explore the relationship between teleology and politics in Kant’s corpus. Among the topics discussed are Kant’s normative political theory and legal philosophy; his cosmopolitanism and views on international relations; his theory of history; his theory of natural teleology; and the broader relationship between morality, history, nature, and politics. _Politics and Teleology in Kant_ will be of interest to a wide audience, including Kant scholars; scholars and students working in (...) moral and political philosophy, the philosophy of history, and political theory and political science; legal scholars; and international relations theorists. (shrink)

The modal account of luck is the predominant account of luck in epistemology and ethics. In the first half of this paper, I discuss three possible interpretations of the modal account and raise objections to each. I then raise an objection to all plausible versions of the modal account, that is, that whether an event is lucky or the extent to which it is a matter of luck will depend on what initial conditions or features of the event one holds (...) constant across nearby possible worlds. However, there is often reasonable disagreement about what the relevant initial conditions of an event are, and the modal account of luck has no means of determining which description of the event is correct. As such, the modal account is subject to a kind of reference class problem, and the view cannot actually tell us the extent to which certain events are a matter of luck. (shrink)

I defend a new version of the non-identity theodicy. After presenting the theodicy, I reply to a series of objections. I then argue that my approach improves upon similar approaches in the literature.

A novel account of virtue signaling and what makes it bad has recently been offered by Justin Tosi and Brandon Warmke. Despite plausibly vindicating the folk’s conception of virtue signaling as a bad thing, their account has recently been attacked by both Neil Levy and Evan Westra. According to Levy and Westra, virtue signaling actually supports the aims and progress of public moral discourse. In this paper, we rebut these recent defenses of virtue signaling. We suggest that virtue signaling only (...) supports the aims of public moral discourse to the extent it is an instance of a more general phenomenon that we call norm signaling. We then argue that, if anything, virtue signaling will undermine the quality of public moral discourse by undermining the evidence we typically rely on from the testimony and norm signaling of others. Thus, we conclude, not only is virtue signaling not needed, but its epistemological effects warrant its bad reputation. (shrink)

Many philosophers, psychologists, and medical practitioners believe that killing is no worse than letting die on the basis of James Rachels's Bare-Difference Argument. I show that his argument is unsound. In particular, a premise of the argument is that his examples are as similar as is consistent with one being a case of killing and the other being a case of letting die. However, the subject who lets die has both the ability to kill and the ability to let die (...) while the subject who kills lacks the ability to let die. Modifying the latter example so that the killer has both abilities yields a pair of cases with morally different acts. The hypothesis that killing is worse than letting die is the best explanation of this difference. (shrink)

One might think that if the majority of virtue signallers judge that a proposition is true, then there is significant evidence for the truth of that proposition. Given the Condorcet Jury Theorem, individual virtue signallers need not be very reliable for the majority judgment to be very likely to be correct. Thus, even people who are skeptical of the judgments of individual virtue signallers should think that if a majority of them judge that a proposition is true, then that provides (...) significant evidence that the proposition is true. We argue that this is mistaken. Various empirical studies converge on the following point: humans are very conformist in the contexts in which virtue signalling occurs. And stereotypical virtue signallers are even more conformist in such contexts. So we should be skeptical of the claim that virtue signallers are sufficiently independent for the Condorcet Jury Theorem to apply. We do not seek to decisively rule out the relevant application of the Condorcet Jury Theorem. But we do show that careful consideration of the available evidence should make us very skeptical of that application. Consequently, a defense of virtue signalling would need to engage with these findings and show that despite our strong tendencies for conformism, our judgements are sufficiently independent for the Condorcet Jury Theorem to apply. This suggests new directions for the debate about the epistemology of virtue signalling. (shrink)

This is a book review of Peter van Inwagen and Dean Zimmerman (eds.), Persons: Human and Divine (Oxford: Oxford Univ. Press, 2007).

People who report believing in God fear death. They also experience grief when someone they love dies. Philosophers and social scientists sometimes claim that this can only be plausibly explained by the hypothesis that people who claim to believe in God do not really believe in God. I show that this is mistaken. I identify three independently plausible explanations of why people who genuinely believe in God would have these behaviors and attitudes. First, there is an evolutionary explanation of why (...) the fear of death would be resilient even if one genuinely believes God has good things in store for us after death. Second, people often fear low probability outcomes. It may be that religious people are afraid of hell or the cessation of existence even if they judge those outcomes to have a low probability. Third, belief in God is typically combined with views according to which death is accompanied by the permanent loss and radical transformation of important relationships. (shrink)

Our question is this: What makes an act one of entrapment? We make a standard distinction between legal entrapment, which is carried out by parties acting in their capacities as (or as deputies of) law- enforcement agents, and civil entrapment, which is not. We aim to provide a definition of entrapment that covers both and which, for reasons we explain, does not settle questions of permissibility and culpability. We explain, compare, and contrast two existing definitions of legal entrapment to commit (...) a crime that possess this neutrality. We point out some problems with the extensional correctness of these definitions and propose a new definition that resolves these problems. We then extend our definition to provide a more general definition of entrapment, encompassing both civil and legal cases. Our definition is, we believe, closer to being extensionally correct and will, we hope, provide a clearer basis for future discussions about the ethics of entrapment than do the definitions upon which it improves. (shrink)

Many philosophers and members of the public think it is wrong to procreate. If one wants children, it is permissible to adopt. But procreation is allegedly impermissible because there is some respect in which adoption is better than procreation. I show that such objections are unsound.

Some feminists hold that surrogacy contracts should be unenforceable or illegal because they contribute to and perpetuate unjust gender inequalities. I argue that in developed countries, surrogacy contracts either wouldn't have these negative effects or that these effects could be mitigated via regulation. Furthermore, the existence of a regulated surrogacy market is preferable on consequentialist grounds.

Some legal theorists say that legal entrapment to commit a crime is incoherent. So far, there is no satisfactorily precise statement of this objection in the literature: it is obscure even as to the type of incoherence that is purportedly involved. (Perhaps consequently, substantial assessment of the objection is also absent.) We aim to provide a new statement of the objection that is more precise and more rigorous than its predecessors. We argue that the best form of the objection asserts (...) that, in attempting to entrap, law-enforcement agents lapse into a form of practical incoherence that involves the attempt simultaneously to pursue contrary ends. We then argue that the objection, in this form, encompasses all cases of legal entrapment only if it is supplemented by appeal to the premise that law-enforcement agents have an absolute duty never to create crimes. (shrink)

Kopeikin (forthcoming a, forthcoming b) and Rachels’ (1975) bare-difference cases elicit the intuition that killing is no different than letting die. Hill’s (2018) bare-difference cases elicit the intuition that killing is worse than letting die. At least one of the intuitions must be mistaken. This calls for an error theory. Hill has an error theory for the intuition elicited by the Kopeikin/Rachels’ cases. Kopeikin and Rachels have an error theory for the intuition elicited by Hill’s cases. A (...) natural thought is that we are at an impasse. There is no plausible basis for preferring one error theory to the other. I argue that this natural thought is mistaken. Not all error theories are equal. Preliminary considerations favor Hill’s error theory and disfavor the Kopeikin/Rachels error theory. But preliminary considerations are not decisive. The way forward in the bare-difference debate is not to evaluate intuitions. The intuitions are in. What is left to do now is evaluate the comparative status of the Hill and the Kopeikin/Rachels error theories. (shrink)

It is often assumed that all lucky events are significant. The thought is that a chancy event such as winning the lottery is lucky for you in part because it affects your interests or well-being. But whether you win an Absurdist Raffle in which there are no prizes, is, intuitively, not a matter of luck. This is because this event—even if chancy—is not significant for any subject. However, a few philosophers have recently claimed not only that luck does not necessarily (...) involve a significance condition but that we should not view luck involving claims in terms of significance. After reviewing the literature on this topic, I argue that lucky events are significant. A significance condition is necessary to distinguish between different kinds of luck: practical, epistemic, and moral. All lucky events are significant and chancy, but they can be significant for subjects in different ways. For example, an event is epistemically lucky for you if it is epistemically significant and chancy, but such events need not affect your practical interests or moral standing. Furthermore, I argue that events that are chancy but not significant should be thought of in terms of chance and not luck. (shrink)

In an important and widely cited paper, Zerilli, Knott, Maclaurin, and Gavaghan (2019) argue that opaque AI decision makers are at least as transparent as human decision makers and therefore the concern that opaque AI is not sufficiently transparent is mistaken. I argue that the concern about opaque AI should not be understood as the concern that such AI fails to be transparent in a way that humans are transparent. Rather, the concern is that the way in which opaque AI (...) is opaque is very different than the way in which humans are opaque. What matters is the degree to which the opaque processes of a class of decision makers are stable, uniform, and safe. The degree to which such processes have these features in humans is higher than the degree to which such processes have these features in opaque AI. And therefore we should require AI to be more transparent than humans. (shrink)